Treatment-related Adverse Effects in MDS: Managing Them Before They Derail Therapy

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Release Date: October 31, 2016
Expiration Date: October 31, 2017

Expected time to complete this activity as designed: 60 minutes

There are no fees for participating in or receiving credit for this online activity.

Program Overview

The optimization of treatment for patients with myelodysplastic syndromes (MDS) is largely dependent on the treatment-related adverse effects of therapy. Practitioners across the multidisciplinary health care provider team must be able to recognize toxicities associated with therapeutic regimens and employ the appropriate management strategies. In this activity, Dr. DeZern will present the most up-to-date information and data concerning proactive and effective management of treatment-related adverse effects in patients with MDS.

Target Audience

This activity is designed for physicians, pharmacists, physician assistants, nurses, and other health care professionals who may provide care to patients with myelodysplastic syndromes.

Learning Objectives

Upon completion of this educational activity, participants should be able to:

  • Recognize treatment-related toxicities in MDS, including serious adverse effects that may require change in therapy
  • Summarize strategies to manage adverse effects and mitigate toxicities in MDS
  • Outline proactive monitoring strategies for at-risk patients, including the elderly and specific comorbidities


Treatment-related Adverse Effects in MDS: Managing Them Before They Derail Therapy – Amy DeZern, MD, MHS

Instructions for Participation and Credit

This activity is eligible for credit through October 31, 2017. After this date, this activity will expire and no further credit will be awarded.

  1. Read the target audience, learning objectives, and faculty disclosures.
  2. You may be asked to complete a short pre-test before accessing the educational content. This must be completed in order to move forward in the activity.
  3. Complete the educational content as designed.
  4. Complete the post-test. To receive a certificate, you must receive a passing score of 70%.
  5. Complete the activity evaluation survey to provide feedback and information useful for future programming.
  6. Certificates CME and CNE may be printed immediately after successfully completing the post-test and activity evaluation. Pharmacist credit will be uploaded to CPE Monitor 4 weeks following receipt of a completed, qualified form.

Faculty Biography

Amy E. DeZern, MD, MHS
Assistant Professor of Oncology and Medicine
Sidney Kimmel Comprehensive Cancer Center
The Johns Hopkins School of Medicine
Baltimore, Maryland

Dr. Amy DeZern received her medical degree from The Johns Hopkins University School of Medicine. She also completed a medical internship and residency, as well as a medical oncology and hematology fellowship at Johns Hopkins. Dr. DeZern received her masters of health science in clinical investigation at Johns Hopkins Bloomberg School of Public Health, followed by a fellowship in medical oncology and hematology at Sidney Kimmel Comprehensive Cancer Center (SKCCC). She is currently an Assistant Professor of Oncology and Medicine at SKCCC at Johns Hopkins University School of Medicine, and is an Attending Physician at The Johns Hopkins Hospital.

Dr. DeZern has American Board of Internal Medicine certification in internal medicine and hematology. She holds memberships in the American Society of Hematology and American Society of Clinical Oncology, and is also involved with the Aplastic Anemia & MDS International Foundation. Dr. DeZern’s clinical and research interests are focused on bone marrow failure disorders and hematologic malignancies. She is the principal investigator of a number of clinical protocols for patients with MDS and aplastic anemia, and her findings have been published in multiple scientific journals and presented at national meetings.


Accreditation Statement: MediCom Worldwide, Inc. is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Designation Statement: MediCom Worldwide, Inc. designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
MediCom Worldwide, Inc. is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. This activity is acceptable for 1.0 contact hour of Continuing Education Credit. Universal Activity Number: 827-0000-16-114-H01-P. Knowledge-based CPE activity.

In order for CPE Monitor to authenticate credit, pharmacists/technicians must provide their e-Profile ID number from NABP and date of birth (in MMDD format) when registering for a CPE program. Please make sure to provide this information in your Member Profile accessed through the login/registration on the home page of this site.
Accreditation Statement: MediCom Worldwide, Inc., 101 Washington Street, Morrisville, PA 19067 is approved by the California Board of Registered Nursing, Provider Number CEP11380. MediCom designates this CNE activity for 1.0 contact hour. Program Number: 16-114-039


As an organization accredited by the Accreditation Council for Continuing Medical Education (ACCME), Accreditation Council for Pharmacy Education (ACPE) and California State Board of Registered Nursing, MediCom Worldwide, Inc. requires everyone who is in a position to control the content of an educational activity to disclose all relevant financial relationships with any commercial interest. The ACCME defines “relevant financial relationships” as financial relationships in any amount, occurring within the past 12 months, including financial relationships of a spouse or life partner, that could create a conflict of interest. Accordingly, the following disclosures were made.

Faculty Disclosure

Dr. Amy DeZern has disclosed no relevant financial relationships.

Planning Committee Disclosures

The individuals listed below from MediCom Worldwide, Inc. reported the following for this activity: Joan Meyer, RN, MHA, Executive Director, and Patrick Brooks, PharmD, Medical Director, Oncology, have no relevant financial relationships.

Peer Reviewer Disclosure

In accordance with MediCom Worldwide, Inc. policy, all content is reviewed by external independent peer reviewers for balance, objectivity and commercial bias. The peer reviewers have no relevant financial relationships to disclose.

Physician Payments, Sunshine Act

MediCom Worldwide, Inc. complies with the Physician Payments Sunshine Act as part of the Affordable Care Act (ACA). Accordingly, we may be required to collect information on transfer of value provided to any covered recipient under the ACA.

Hardware/Software/Internet Requirements

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If you have any questions or concerns regarding this activity, please contact MediCom Worldwide, Inc. at 1-800-408-4242 or email us at

Provided by MediCom Worldwide, Inc.
This activity is supported by an educational grant from Celgene Corporation

©2016 MediCom Worldwide, Inc., 101 Washington St., Morrisville, PA 19067, 800-408-4242.
No portion of this material may be copied or duplicated without the expressed permission of MediCom Worldwide, Inc.

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