Practical Applications of the IPSS-R in MDS

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Release Date: December 10, 2015
Expiration Date: December 10, 2016

Expected time to complete this activity as designed: 15 minutes
There are no fees for participating in or receiving credit for this online activity.

Program Overview

Myelodysplastic syndromes (MDS) are clonal disorders primarily of the elderly that are characterized by ineffective hematopoiesis and increased risk of transformation to acute myeloid leukemia (AML). MDS are considered clinically heterogeneous conditions because they can present with widely varying degrees of severity and because patients with similar features at diagnosis can have large differences in how their disease evolves over time.

There have been significant advances across many aspects of MDS including diagnosis (development/investigation of new diagnostic techniques), classification (new classification criteria have been developed), prognostic scoring systems (developed and validated), and new treatments have been approved.

This MDS Quarterly e-Newsletter focuses on the role of the Revised International Prognostic Scoring System (IPSS-R) in daily clinical practice, specifically with regard to identifying prognosis for individual patients and selecting treatment based on prognostic score. This activity also addresses the practical aspects of delivering prognostic information to patients and/or their caregivers.

Target Audience

This activity is designed for physicians, pharmacists, and physician assistants who have an interest in enhancing their clinical skills in the management of patients with myelodysplastic syndromes (MDS).

Learning Objectives

Upon completion of this educational activity, participants should be able to:

  • Interpret the rationale for risk stratification in MDS, focusing on the correlation between a treatment strategy individualized for a patient’s specific risk and improved outcomes
  • Summarize the IPSS-R, correlating IPSS-R scores with prognosis in MDS
  • Recognize the components of a strategy for effectively communicating the results of a prognostic risk stratification to a newly diagnosed MDS patient, and the impact this stratification will have on their treatment


Practical Applications of the IPSS-R in MDS – Tania Dickson, PhD, and Eugene R. Tombler, PhD, FACME

Instructions for Participation and Credit

This activity is eligible for credit through December 10, 2016. After this date, this activity will expire and no further credit will be awarded.

  1. Read the target audience, learning objectives, and faculty disclosures.
  2. You may be asked to complete a short pre-test before accessing the educational content. This must be completed in order to move forward in the activity.
  3. Complete the educational content as designed.
  4. Complete the post-test. To receive a certificate, you must receive a passing score of 70%.
  5. Complete the activity evaluation survey to provide feedback and information useful for future programming.
  6. Certificates for CME credit may be printed immediately after successfully completing the post-test and activity evaluation. Pharmacist credit will be uploaded to CPE Monitor 4 weeks following receipt of a completed, qualified form.

Contributing Author Biographies

Tania Dickson, PhD
Content Solutions

Dr. Tania Dickson graduated from Monash University in Melbourne, Australia, with a class I honors bachelor of science degree, majoring in biochemistry. She received her doctor of philosophy degree from the Institute of Reproduction and Development in Melbourne, prior to completing a 4-year postdoctoral fellowship at the Vanderbilt Cancer Center, Nashville, Tennessee. Dr. Dickson has over 15 years of medical writing and medical direction experience and is knowledgeable in the preparation of scientific content for Continuing Medical Education across numerous print and multimedia modalities.

Eugene R. Tombler, PhD, FACME

Dr. Gene Tombler received his PhD in Biomedical Sciences as a Public Health Service grant trainee within the Molecular, Cellular, Biochemical and Developmental Sciences Program at the Mount Sinai School of Medicine of NYU. He has an extensive interdisciplinary background in the biomedical sciences and more than 15 years’ experience in oncology. He has served as a medical writer, publication planner, and medical director in both educational and promotional medical communications. Gene has developed oncology programs for prostate, breast, ovarian, lung, liver, and kidney cancers, as well as for hematologic malignancies including AML, CML, non-Hodgkin’s lymphoma, and multiple myeloma.


Accreditation Statement: MediCom Worldwide, Inc. is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.
Designation Statement: MediCom Worldwide, Inc. designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
MediCom Worldwide, Inc. is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education. This activity is acceptable for 0.25 contact hours of Continuing Education Credit. Universal Activity Number: 827-0000-15-060-H01-P. Knowledge-based CPE activity.

In order for CPE Monitor to authenticate credit, pharmacists/technicians must provide their e-Profile ID number from NABP and date of birth (in MMDD format) when registering for a CPE program. Please make sure to provide this information in your Member Profile accessed through the Member Center on the home page of this site.


As an organization accredited by the Accreditation Council for Continuing Medical Education (ACCME), Accreditation Council for Pharmacy Education (ACPE) and California State Board of Registered Nursing, MediCom Worldwide, Inc. requires everyone who is a position to control the content of an educational activity to disclose all relevant financial relationships with any commercial interest. The ACCME defines “relevant financial relationships” as financial relationships in any amount, occurring within the past 12 months, including financial relationships of a spouse or life partner, that could create a conflict of interest. Accordingly, the following disclosures were made.

Contributing Author Disclosures

Dr. Tania Dickson and Dr. Eugene Tombler have disclosed no relevant financial relationships.

Planning Committee Disclosures

The individuals listed below from MediCom Worldwide, Inc. reported the following for this activity: Joan Meyer, RN, MHA, executive director, has no relevant financial relationships.

Peer Reviewer Disclosure

In accordance with MediCom Worldwide, Inc. policy, all content is independently peer reviewed for balance, objectivity and commercial bias. The peer reviewers have no relevant financial relationships to disclose.

Off-Label Disclosures/Investigational Disclosures

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The opinions expressed in the educational activity are those of the faculty. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings. Further, attendees/participants should appraise the information presented critically and are encouraged to consult appropriate resources for any product or device mentioned in this program.

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Provided by MediCom Worldwide, Inc.
This activity is supported by an educational grant from Celgene Corporation.

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No portion of this material may be copied or duplicated without the expressed permission of MediCom Worldwide, Inc.

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